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Calcium Chloride Dihydrate USP BP EP Grade

Character: It is white or almost white, crystalline powder or granule, hygroscopic. It is freely soluble in water, soluble in ethanol (96 percent).

Product Description

1. Product name: calcium chloride dihydrate

2. Molecular Formula: CaCl2·2H2O

3.Synonyms:Sinjarite;replenisher(calcium);Calcium chloride dih;CALCIUM CHLORIDE 6H2O;CalciumCitrateExtraPure;Calciumchloride,granular;CalciumChlorideHydratedIp;alcium chloride dihydrate;Calcium chloride dihydrate;CalciumChlorideDihydrateAr

4. Molecular Weight: 147.01

5. CAS: 10035-04-8

6. Character: It is white or almost white, crystalline powder or granule, hygroscopic. It is freely soluble in water, soluble in ethanol (96 percent).

7. Application: calcium supplement; use in the manufacture of dialysis solutions and etc.

8. Packing: 25kg paper bag or customized package.

Calcium chloride dihydrate Properties

Melting point:30 °C
Density 1.71 g/mL at 25 °C(lit.)
vapor pressure 0.01 mm Hg ( 20 °C)
refractive index ~1.358
storage temp. Store at +15°C to +25°C.
solubility H2O: 1 M at 20 °C, clear, colorless
form Solid
color White to white-grayish
Specific Gravity0.835
PH4.5-8.5 (50g/l, H2O, 20℃)
PH Range5 - 8
Water Solubility 1000 g/L (0 ºC)
λmaxλ: 260 nm Amax: 0.015
λ: 280 nm Amax: 0.012
Sensitive Hygroscopic
Merck 14,1659
Stability:Stable. Hygroscopic. Incompatible with vinylmethyl ether.

Calcium Chloride Dihydrate Properties, Uses and Production Technology


Calcium chloride dihydrate (CaCl2﹒2H2O) is the hydrated form of calcium chloride. Calcium chloride is an inorganic compound composed of calcium and chloride. It has various applications. For example, due to its high hygroscopicity, it can be used as a desiccant; for deicing and dust removal; for pavement; as a brine for refrigeration equipment, ice and cement; to increase the hardness of swimming pool water; as a food additive; to increase cell membrane permeability Sex to promote genetic transformation of cells; used to treat hypocalcemia where the body requires a rapid increase in plasma calcium levels. For its production, it can be produced directly from limestone or as a by-product through the Solvari process.


Calcium chloride is a general-purpose food additive that is readily soluble in water in anhydrous form, with a solubility of 59 g in 100 ml of water at 0°C. It dissolves with the release of heat. It also exists in the form of calcium chloride dihydrate and is extremely soluble in water, with a solubility of 97 g in 100 ml at 0°C. It is used as a curing agent for canned tomatoes, potatoes and apple slices. In evaporated milk, it is used at no more than 0.1% to adjust the salt balance to prevent the milk from curdling during the sterilization process. It is used with disodium EDTA to preserve the flavor of kimchi and acts as a source of calcium ions to react with alginate to form a gel.

chemical properties

Calcium chloride is a colorless to off-white crystalline solid that is deliquescent (hygroscopic). Crystals lose water at 100 C when heated.

Cosmetic ingredients

Food grade calcium chloride is used in a variety of applications in the food and beverage industry.
In the production of beer and soft drinks, calcium chloride is used as a source of calcium to adjust the hardness of water.
In cheese production, CaCl2 is used as a source of calcium.
CaCl2 is also used to increase the firmness of canned fruits and pickled vegetables.
CaCl2 is also used as an auxiliary coolant in various processes operating in accordance with food regulations.

Biological Functions

Calcium chloride is a commonly used reagent in biochemistry. Calcium plays important roles in many biological processes, including signal transduction, muscle contraction, and maintenance of cell membrane and cell wall stability.Extensive reviews of the experimental measurement of biological calcium have been published.
Calcium chloride is used in the preparation and transformation of competent E. coli and in the transfection of eukaryotic cells with either plasmid DNA or high molecular weight genomic DNA.The CaCl2-mediated electroporation of E. coli with the plasmid DNA pBR322 has been studied.A protocol for the concentration of virus vectors that uses CaCl2 has been published.
CaCl2 has been used in the stabilization and twodimensional crystallization of the NADH-ubiquinone oxidoreductase (complex I) from Escherichia coli. The crystallization of porcine pancreatic elastase in the presence of CaCl2 in the presence of sodium citrate reveals binding of calcium in the metal binding site of the protein.The effect of CaCl2 on the total fluorescence in the polymerication of the tubulin-like FtsZ division protein of Escherichia coli has been studied by a multiwell fluorescent assay.

Biochem/physiol Actions

Calcium chloride act as precipitants during protein crystallization process. It also enhances the competence of Escherichia coli cells as well as strengthened β-lactoglobulin gels by forming crossbridges.

Purification Methods

Crystallise it from ethanol. It is hygroscopic. It loses H2O at 200o so it can be dried at high temperatures to dehydrate it. The hexahydrate [7774-34-7] has m 30o and d 1.67.


Product parameter

Test item USP 40 EP
Identification Passes test Passes test
Content (CaCl2·2H2O) 99.0-107.0 % 97.0-103.0 %
Acidity or Alkalinity --- Passes test
Sulfates --- 300 ppm
Aluminium 1 ppm 1 ppm
Barium --- Passes test
Iron --- 10 ppm
Magnesium and alkali metals 1.0 % 0.5 %
Heavy metals 10 ppm 20 ppm
Iron, aluminium and phosphate Passes test ---
pH 4.5-9.2 ---



Product Pictures


Calcium Chloride Dihydrate

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